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KMID : 0363819700040020029
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Korean Journal of Nuclear Medicine
1970 Volume.4 No. 2 p.29 ~ p.39
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Clinical Investigation and Treatment of Thyroid
Diseases with Radioactive Iodine (^(131)I)
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Abstract
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Fourteen patients with typhoid fever were studied by scanning and clearance-rate measurements of subcritical dose colloidal radiogold ("´Au).
Mild to moderate enlargement of the liver and spleen was noted in 78. 6 and 64. 3 per cent of patients, respectively; and splenic and spinal bone-marrow uptake was seen in 78. 6 and 57. 1 per cent of cases, respectively. Typically, these scan changes occurred concomitantly (57.1%) and are considered to represent increased phagocytic activity of the RE cells which is characteristic of typhoid fever. The half clearance-time was significantly shortened during the first 10-day period of
the illness indicating an increas in the hepatic blood in the early phase of typhoid infection. Hepatomegaly, splenomegaly and eatrahepatic uptakes along with an accelerated (or later a normal) clearance time are characteristic of typhoid fever.
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KEYWORD
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